Results from NY’s Hydroxychloroquine and Zithromax Drug Trials Due Out Today

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Why isn’t anyone talking about this? Where are the media queries? Governor Cuomo has been suspiciously silent on the drug trials, the media even less curious. The rare question about the hydroxychloroquine trials is met with the same vague answer, anecdotal evidence is “encouraging” and results will be released on April 20.

Clinical trials began March 24.

Will one reporter interrupt Cuomo’s cracker barrel hour to ask a probing question — what do the drug trials show?

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Today it is being reported:

Novartis has won the go-ahead from the U.S. Food and Drug Administration to conduct a randomized trial of malaria drug hydroxychloroquine against COVID-19 disease, the Swiss drugmaker said on Monday, to see if it helps patients.

The decades-old generic medicine got FDA emergency use authorization this month for its unapproved use for coronavirus disease. “We recognize the importance of answering the scientific question of whether hydroxychloroquine will be beneficial for patients with COVID-19 disease,” said John Tsai, Novartis’s top drug developer. “We mobilized quickly to address this question in a randomized, double-blind, placebo-controlled study.”

Novartis’s Sandoz generics unit has pledged to donate 130 million doses of the medicine for use. Sanofi has also said it will donate 100 million doses of hydroxychloroquine to 50 countries.

Researchers in New York will announce new week the preliminary results of a study on hydroxychloroquine, a drug often touted by President Trump as a “game-changer” for coronavirus patients.

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The announcement could offer one of the first scientific hints as to whether the drugs are helpful against the virus.

Since hydroxychloroquine is already on the market for malaria, lupus and other diseases, doctors are free to prescribe it “off label” to patients with coronavirus. Doctors can also prescribe chloroquine, a similar drug, and azithromycin, an antibiotic that’s sometimes paired with the two drugs.

The New York study will review hundreds of medical records from hospital patients across New York state with coronavirus to see if the drugs are helping them or hurting them.

In clinical trials, which are considered the gold standard in medicine, doctors give the drugs to a group of patients and then give placebo pills to another group of patients, and compare how the two groups fare. There are more than a dozen clinical trials underway in the US right now but results for most of them won’t be published for months.

The Albany medical records study is being conducted in partnership with the New York Department of Health, which is funding the study.

Related: Uganda is successfully  treating Coronavirus patients with Hydroxychloroquine

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