HYDROXYCHLOROQUINE and AZITHROMYCIN

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https://twitter.com/realDonaldTrump/status/1241367239900778501

 

New drug combo wiped out coronavirus in patients

By Mike Wehner, BGR, March 20th, 2020:

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A combination of two existing drugs is proving to be effective at eliminating the novel coronavirus in patients confirmed to have the infection.

Treatment with both hydroxychloroquine, an anti-malaria drug, and the antibiotic azithromycin dramatically shortened the recovery time for people with COVID-19.

More trials on a larger scale will be needed before we know just how effective this drug combo is.
Visit BGR’s homepage for more stories.

A specific combination of existing drugs has shown it is capable of wiping out the novel coronavirus in a small-scale study conducted in France. Doctors gave confirmed COVID-19 patients a drug cocktail that included the anti-malaria drug hydroxychloroquine and the antibiotic azithromycin. The results of the trial were published in the International Journal of Antimicrobial Agents.

A total of 30 COVID-19 patients participated in the trials. The participants were split into three groups. Ten of the patients received just the anti-malaria drug, while another group of ten receive both hydroxychloroquine in combination with the antibiotic. The third group of 10 were the control group and did not receive any treatment.

Remarkably, the anti-malaria medication proved to significantly reduce the duration of the infection in the patients who received it, but the combination of both drugs produced truly astounding results. In fact, by the fifth day of treatment, all of the patients who received the drug combo tested negative for the active virus.

The test is indeed promising, but it was so small in scale that it’s difficult to know how much stock to put in it. A much larger test would give us a more accurate idea of how effective these treatment options are, but it’s hard not to feel optimistic about it based on these results.

This is hardly the only drug trial to examine the effectiveness of existing medications on COVID-19 patients, and there have been several experimental treatments that show promise. A flu drug from Japan may be effective in treating patients, based on a report from China earlier this week, while other institutions are experimenting with the blood pressure drug losartan to see if it can prevent the virus from infecting patients in the first place.

What allowed the COVID-19 pandemic to cause such a disruption in our lives is that we know so little about it. No, it’s not the most deadly virus in the world, not by a long shot, but it’s extremely contagious and spreads rapidly through a population. Finding drugs that work to combat that spread is vital, and it’s only natural that we try existing options first while other drugs built specifically for this illness are in development.

For now, practicing social distancing and heeding the advice of health officials to stay home and avoid each other are the most important things we can do to slow the outbreak. Giving our healthcare systems room to breathe and not burying hospitals under a flood of patients will help mitigate serious consequences, and that responsibility is shared equally by all of us.

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Bonnie Pupowner
Bonnie Pupowner
4 years ago

Its called off label prescribing.
Been done forever.
Drs know what a drug works for besides what the FDA states.

DemocracyRules
DemocracyRules
4 years ago

Yes, the FDA can be bypassed in this case. These meds are already proven safe and effective for other uses, and approved by the FDA. Most physicians can prescribe existing meds ‘off-label’ for other indications like this one. The hydroxychloroquine fights the Covid-19 virus, and the azithromycin fights the pneumonia bacteria. We will see some docs writing scrips for these meds today. It’s horrible to watch patients pass away from severe pneumonia. And anything is worth a try at that point.

Achmed Mohandjob
Achmed Mohandjob
4 years ago
Reply to  DemocracyRules

I wonder how well does that sh-t go with gin?

DemocracyRules
DemocracyRules
4 years ago

We discussed that already! Those chloroquine pills are really really bitter!

Achmed Mohandjob
Achmed Mohandjob
4 years ago
Reply to  DemocracyRules

No, we discussed quinine water v tonic water. So, if gin is used, it could be called gin,quinine, and bitters(?).

DemocracyRules
DemocracyRules
4 years ago

Oh man, chloroquine is bitter like you would not believe! One cannot chew those pills, or the taste will persist for hours.

Achmed Mohandjob
Achmed Mohandjob
4 years ago
Reply to  DemocracyRules

OK. OK. OK …. You have me. What, in the world, were you doing chewing tablets of Hydroxychloroquine?

DemocracyRules
DemocracyRules
4 years ago

Well, it’s a long story…

Achmed Mohandjob
Achmed Mohandjob
4 years ago
Reply to  DemocracyRules

Now, THAT’S funny!

Poppey
Poppey
4 years ago

The anti malaria drug combination with the antibiotic sounds very promising, but a prudent student of history would think a moment and then ponder what happens on day two when the problem bug mutates, what are you going to hit it with then ?

DemocracyRules
DemocracyRules
4 years ago
Reply to  Poppey

The antimalarial chloroquine seems to be quite generic for coronaviruses in general. Even if the Covid-19 mutates, the hydroxychloroquine might help.

Here’s a link to the actual peer-reviewed published study, in English:
https://drive.google.com/file/d/186Bel9RqfsmEx55FDum4xY_IlWSHnGbj/view
You can download it and/or print it, and have it ready to shove into your doctor’s hands. Docs are used to getting internet stuff from patients, but his one comes from the ‘International Journal of Antimicrobial Agents’, a respected science journal.

Public_Citizen
Public_Citizen
4 years ago
Reply to  Poppey

Chloroquine and its derivatives seem to have an effect on all the Corona Virus strains so it is unlikely the virus can mutate into a form that would be immune to the effects of this drug.

If I understand what is going on, one of the effects of chloroquin is to push the bodies ph towards the acidic end of the normal range, making it more difficult for the virus to survive in the human body. It seems to weaken the outer protein layer so that the bodies own defenses can easily penetrate and disrupt the portion of the virus that makes it reproduce.

Mohammed_Goldberg
Mohammed_Goldberg
4 years ago

And there are many voices in congress are yelling “me first”…..

DemocracyRules
DemocracyRules
4 years ago

Yes, but every pharmacy sells these, most physicians can prescribe them, and the meds cost less than $20.

DemocracyRules
DemocracyRules
4 years ago
Reply to  DemocracyRules

Breaking: FDA Authorizes First 45-Minute ‘Rapid Point-Of-Care’ Test for Covid-19 virus
https://www.zerohedge.com/geopolitical/fda-authorizes-first-45-minute-rapid-point-care-test
“The FDA announced Saturday that it has approved a rapid “point-of-care” test for COVID-19 that can produce results for patients within 45 minutes. The agency approved the test late Friday, and on Saturday announced that it had granted the first approval a California company that will have the tests commercially available by the end of March. The FDA granted “emergency use authorization” to Cepheid, a Cali-based company that makes a rapid molecular test for the coronavirus. Getting results in 45 minutes would be far quicker than the current situation in which tests typically are sent to central reference labs that can take days to deliver results.”

felix1999
felix1999
4 years ago
Reply to  DemocracyRules

It is amazing what is being accomplished with these lethargic, age old government
bureaucracies . That is Trump’s doing.

Poetcomic1
Poetcomic1
4 years ago

Nigeria has…three cases, one of them an Italian traveler and the other infected by the Italian. The third is doing well. This is the heart of the ‘malaria belt’ where hydroxocholroquine is gobbled down like candy. Other countries in the malaria belt where this drug is commonly used seem to demonstrate a ‘prophylactic’ effect in which people do not get the virus if they had used the drug in the past.

DemocracyRules
DemocracyRules
4 years ago
Reply to  Poetcomic1

South Korea is still tailing off. The total number of cases who were ever infected is leveling off [purple]. Meanwhile, the number who have recovered is increasing [green], and so the number who are still infected is dropping off [yellow].
comment image
Japan and Scandinavia also show similar patterns.

DemocracyRules
DemocracyRules
4 years ago
Reply to  Poetcomic1

“The best thing for your personal environment is a diffuser with antiviral essential oils. common sense”– NOT clinically recommended. Oils can harbor viruses and bacteria. Watery droplets and aerosols naturally precipitate out of the air, because they are heavier than air. Separation, and self-isolation are recommended, and N95 masks are recommended for high aerosol environments.

Jeff Ludwig
Jeff Ludwig
4 years ago

God knows I’m praying that this will be the answer. I was already rehearsing a scenario in my mind where I insist on these drugs to some stubborn stupid medical personnel. Funny. Why isn’t this info about Dr Grace in every front page as well as the French study. I told myself that I needed to go to this site for a dose of reality before going to sleep!! The

felix1999
felix1999
4 years ago
Reply to  Jeff Ludwig

Some people don’t trust studies done by foreign countries.

whitefalcon74
whitefalcon74
4 years ago

HYDROXYCHLOROQUINE Symptoms.
Patients in earlier stages of hydroxychloroquine retinal toxicity
usually do not experience symptoms, though the rare patient may note a paracentral scotoma that causes trouble with reading as well as diminished color vision. However, most patients usually notice symptoms only after scotomas have become severe. When allowed to advance, hydroxychloroquine retinal toxicity leads to loss of up to three visual functions: acuity, peripheral vision and night vision.Signs

Public_Citizen
Public_Citizen
4 years ago

Similar effects are being reported around the world.
We need to get ahead of this by prescribing Chloroquine on a prophylactic basis, starting with the elderly and any other people with compromised Immune Systems first and working down the categories of those at risk until most of the population is a kill zone for the virus instead of walking incubators.

If we can get to a high enough level of prophylaxis the virus will burn itself out and work on a vaccine can proceed without the current level of panic that too many people are experiencing.
Hopefully, this will result in the development of a broad spectrum Corona Virus Vaccination that will be effective either as is or with slight tweaks against a whole range of these viruses.

Drew the Infidel
Drew the Infidel
4 years ago

The last time I had the flu many moons ago, I cured it quickly with single doses of Seagrams VO and water. It works.

John Acord
John Acord
4 years ago

Great, we have a prophylactic and maybe a cure for the CCP Virus now we have to repair the economic destruction caused by the deliberate release of the CCP Virus. First, the evidence which I have previously published here is overwhelming that the CCP most probably in alliance with the short-sellers aligned with Soros and Bloomberg made hundreds of billions off the market crash. Those funds have to be frozen and clawed back and the rest of their wealth seized for damages. China must be blockaded and sanctioned and every effort made to collapse their economy so that the people can rise up and cast out the murderous CCP.

Patriotliz
Patriotliz
4 years ago

I don’t understand why all health care professionals, hospital workers, emergency personnel and police aren’t already having mandatory testing for COVID19, even if they’re asymptomatic. They could be carriers of the virus. If positive for COVID19 they all have to be quarantined and offered Rx with Plaquenil and Azithromycin to try to get rid of the virus and become negative for the virus before going back to work. Then that should be implemented for the public in general.

I don’t think Dr. Fauci is acting with any real urgency as a “clinician.” I have yet to hear TREATMENT protocol recommendations for those doctors in the trenches trying to deal with this public health medical emergency which is causing an acute “economic” emergency. I think Dr. Fauci and Dr. Birx are too bureaucratized. America doesn’t have time to wait for a vaccine or a double-blind NIH clinical study for treatment protocol.

I wonder why none of the “astute” reporters at the press conferences don’t bring up these issues at the daily press conferences. Instead of attacking Trump and his hopeful messaging, why don’t they attack Dr. Fauci and the other medical doctors on the team and put their feet to the fire to come up with treatment protocol recommendations—NOW!

Which antiviral therapies…NOW…what dosing?
What about Vit.C, Vit.D3?
What about quercetin (zinc ionophore) in foods and supplements?
It’s nice to have telemedicine…but what good is it if the docs don’t have universal therapeutic recommendations if you are positive for Covid19? Is Plaquenil and Azithromycin readily available in the pharmacies or are doctors hoarding or over-prescribing to patients demanding it?

AZ gal
AZ gal
4 years ago

I have heard that anti-malaria drug was a problem for our soldiers & perhaps increased PTSD somehow. Why didn’t they do a trial with just the antibiotic?

AC
AC
4 years ago
Reply to  AZ gal

That was mefloquine, which if I recall accurately, the military started using back in 1989 or so, before Desert Storm. Personnel deployed to sub-Saharan Africa in malaria zones were give the drug. It was said to cause symptoms that seemingly mimic those of PTSD.

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